Our Founding Story

Our Founding Story

ICCA Global Cancer Centers: Revolutionizing Cancer Treatment with a Personal Touch

Founded by Gregory DiRienzo in honor of his late wife Joyce Bailey, ICCA Global is making waves in the world of cancer treatment. Based in Southern California, this U.S.-based corporation is driven by a heartfelt mission to provide innovative and integrative therapies to patients from all around the globe.

FivePOINTS Cancer CareJoyce's struggle with intraductal breast cancer at the young age of 39 inspired the creation of ICCA Global. Joyce started her cancer journey in top US based hospitals. She at one point even underwent an aggressive and highly painful bone marrow transplant only to have her cancer return in 2008, prompting a shift towards a more holistic and patient-centered approach. Seeking alternative methods used in other countries, Joyce visited ICCA's German clinics, ultimately beating stage IV breast cancer for an astonishing 27 years. Her victory inspired the mission of ICCA Global: to provide personalized care and access to transformative treatments that heal patients through unconventional, less -toxic treatments from around the world.

"I continually witnessed the United States healthcare system fail my wife and from that day on Joyce moved away from conventional therapy to a more integrative approach. Our focus was on “out of the box” methods that other countries were using to treat cancer patients. Treatments created to heal the patient, not poison."

In early 2012, Greg underwent a regular colonoscopy only to find out it was far from routine. He was diagnosed with Stage 2 kidney cancer. Like all cancer diagnoses, fear and sadness set in but he too, like Joyce, believed in the power of immunotherapy and regenerative medicine as opposed to the typical standard of care used in the United States. Greg underwent a cryoablation at University of Irvine, his immunotherapy was completed in his clinic in Mexico and regenerative therapies performed in Germany. To date, Greg has no evidence of disease!

Since 2009, ICCA Global has been at the forefront of personalized cancer treatments and regenerative medicine, offering hope to patients from all corners of the world. Its affiliate clinics in Germany have become renowned for their expertise in treating all stages of cancer. In 2015, ICCA Global expanded its reach with the opening of a cutting-edge cancer clinic in Baja, Mexico, providing unparalleled care in a luxurious setting.

In the continued quest for innovative therapies, ICCA Global reached an exciting milestone in 2016. Gregory, as an Advisory Trustee to the Western University of Health Sciences Graduate School of Biological Sciences, discovered a groundbreaking cancer therapy from China. Named "Tumor-Targeted Chemo Immunotherapy." This revolutionary approach directly targets solid tumors, bypassing the systemic methods favored by most Western cancer centers.

With a dedication to personalized care with a whole-body approach and innovative therapies, ICCA Global is leading the way in cancer treatment. Together, we can rewrite the narrative of cancer, offering hope, healing, maintaining quality of life and a brighter future.

If you or a loved one is battling cancer, contact us today at +1 (949) 939-0050 or fill out this form to learn more about how ICCA Global can help you on your healing journey.

Restoring Hope. Restoring Life.

Give us a call today to see what our team can do for you and your loved ones.

+1 (949) 939-0050

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ICCA Global Offers HOPE when HOPE is Lost!

Patient Stories

Meet some of our inspiring patients who have found renewed health through our cutting-edge integrative and alternative cancer therapies at ICCA Global. Click here to read more.

Eric L.Liver Cancer Patient

"I am absolutely delighted with the results of the FivePOINTS Cancer Care ™ treatment program provided by ICCA Global. My sincerest thanks go to the Doctors and the medical team, who custom designed and administered an amazing treatment plan that, in my mind, could not have been more successful."

TanyaBreast Cancer Patient

"It's been a year and a half, and I'm still clear, and I'm going to stay clear. If I was to ever go for something like that again, I would hands down go back to ICCA Global. They're just one of a kind, truly, from the treatments that's not done anywhere else, to the facility, staff, doctors, everybody involved are just absolutely amazing, five-stars. And I would recommend ICCA any day. If you're hesitant or nervous or scared, don't be, give them a chance. Call them, consult with them. Just know that the place is real and it's amazing. I have no regrets, it was the best decision of my life."

GiannaPatient's Family Member

"My sister came to ICCA Global with colon to liver, to lungs two years ago - and very near death. She is 100% cancer free today."

Bernie B.Patient's Wife

"I brought my husband to ICCA Global for stage 3 lung cancer that spread to the lymph nodes, and he's doing extremely well. He went through three weeks of treatment and he was not sick a day. Not once. Their standards as far as cancer treatment goes, are superior."

* Each patient is unique, and their treatments are tailored accordingly. Individual results will vary. Please consult your doctor before making any changes to your medical treatment. Not every patient is a candidate for care or achieves these results.

What Makes Us Different?

We believe in giving every patient the chance they deserve, even when others have deemed their case as untreatable. Utilizing global modalities, our Primary, Metastatic and Recurrent Cancer Programs are designed to provide access to life-changing therapies that are often unavailable to patients in the U.S. or Canada. As a truly integrated center, not limited by NCCN guidelines, it enables us to personalize cutting-edge alternative therapies with a higher potential of helping you progress towards healing. With affiliates in Southern California and our treatment center in Baja California, Tijuana Mexico, we're always at the forefront of integrative care.

Join us in paving the way for a new era in cancer treatment. Explore a world of possibilities at ICCA Global, where innovation and hope go hand in hand.

Upon arrival, the patient will undergo a real-time PET/CT scan to address the limitations of a CT scan in detecting potential metastatic cancer at the molecular level. This will be followed by a thorough physical examination, comprehensive lab work that includes specific tumor markers, and an aspirated biopsy if necessary.
Unlock the Potential of Off-Label Medications in Immunotherapy
Discover the untapped power of repurposed medications to supercharge your immune response. By utilizing medications traditionally used for other conditions, we can enhance the effectiveness of immunotherapy.


Maximize Immunotherapy Potential with Microbiome Enhancement
Uncover a groundbreaking approach to treating leaky gut syndrome. By enhancing the microbiome, we can unlock the full potential of immunotherapy, leading to improved outcomes for patients.

Conquer Immunotherapy Challenges with Hypoxia Tumor Targeting
Address the root causes of immunosuppression, treatment resistance, tumor growth, and metastasis with hypoxia tumor targeting. This innovative strategy aims to generate global control over these challenges, revolutionizing the field of immunotherapy.

Revolutionize the Tumor Microenvironment with Heat Therapy
Enhance the effectiveness of systemic immunotherapy by "heating up" tumors. By injecting specific immune agents directly into tumors, we can attract immune cells, ensuring optimal treatment results.

Strengthen the Immune System with Autologous Dendritic Cell Vaccine
Prevent the spread of cancer cells and stimulate the immune system with the pioneering autologous dendritic cell vaccine. By training the immune system to recognize and fight invading cancer cells, we can unleash its full potential.

Enhance Healing with Systemic Detoxification
Complement the body's natural healing processes by removing harmful metals and minerals accumulated from external pollutants. Systemic detoxification supports overall health and strengthens the immune system.

Targeted Therapies for Cancer Cells, While Preserving Vital Tissues
Experience the power of toxic-free therapies that selectively target cancer cells without compromising the immune system or causing debilitating side effects. These innovative treatments work in harmony with the body to bolster its defenses.

Precision Testing to Stay One Step Ahead of Immunotherapeutic Escape.
Stay ahead of cancer's adaptive mechanisms and personalize immunotherapy with advanced testing. Discover specific immunotherapies that can overcome escape mechanisms and adapt treatment strategies for better outcomes.
By carefully administering minimal doses of a chemo-sensitizing agent, we can dramatically enhance the overall effectiveness of treatment. With fewer than 10 brief sessions, you'll witness remarkable results while preserving the integrity of surrounding tissues and organs.
Introducing an innovative technique known as tumor ablations, which effectively eradicates a wide range of cancerous tumors by harnessing the power of microwave energy, extreme heat or cold.

Tumor ablations are an alternative to conventional cancer treatment methods such as chemotherapy and surgery, which are invasive and can have debilitating side effects. With ablations, patients can avoid repeated dosing of chemotherapy or the long-term effects of radiation. Tumor ablations are relatively easy and well-tolerated. The recovery time is much faster and less invasive compared to surgery.

Ablation therapy helps to eliminate these tumors locally which prevents tumors from spreading further. Even more, ablation therapy can help to slow the growth of cancerous cells, reduce symptoms and improve the patient's quality of life.

Through this cutting-edge procedure, a surgeon can easily access the tumor by inserting a small laparoscopic port or open incision. To ensure precision, a CT scan or ultrasonic guidance is employed to accurately locate the tumor. Learn more at tumorablations.com.
In the field of precision medicine, there is a need to address the damage caused to cellular tissues and organs by cancer and its treatment. This can be achieved through the replacement, restoration, or revitalization of these compromised areas.

Our approach to supporting this process is through nutritional and supplemental counseling. By analyzing the individual patient's metabolomic signatures using blood-derived mass spectrometry, a comprehensive understanding of their metabolites can be obtained.

This emerging technology has the potential to inform and enhance the practice of precision medicine, offering new possibilities for improving patient outcomes, to repair and rejuvenate cellular tissues and organs that have been affected by cancer or the side effects of cancer treatment.
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